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1

Review: The Pharmacology of Dobutamine

Ruffolo, Robert R.

Journal:

The American Journal of the Medical Sciences

Année:

1987

Langue:

english

Fichier:

PDF, 4.74 MB

english, 1987

2

Drug Discovery in the Next Millennium

Ohlstein, Eliot H., Ruffolo Jr, Robert R., Elliott, John D.

Journal:

Annual Review of Pharmacology

Année:

2000

Langue:

english

Fichier:

PDF, 114 KB

english, 2000

3

New concepts in α-adrenoceptor pharmacology

Robert R. Ruffolo Jr., J. Paul Hieble

Journal:

Pharmacological Research

Année:

1995

Langue:

english

Fichier:

PDF, 161 KB

english, 1995

4

Stereochemical studies of adrenergic drugs. Optically active derivatives of imidazolines

Miller, Duane D., Hsu, Fu-Lian, Ruffolo, Robert R., Patil, Popat N.

Journal:

Journal of Medicinal Chemistry

Année:

1976

Langue:

english

Fichier:

PDF, 336 KB

english, 1976

5

Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques || Pharmacology of synthetic organic selenium compounds

Parnham, Michael J., Graf, Erich, Kolb, Vera M., Seth, Renu, Sinha, Shradha, Ruffolo, Robert R., Hieble, J. Paul, Brooks, David P., Feuerstein, Giora Z., Nichols, Andrew J., De Benedetti, P. G., Jucke

Année:

1991

Langue:

english

Fichier:

PDF, 3.67 MB

english, 1991

6

Disease-modifying effects of phosphocitrate and phosphocitrate-β-ethyl ester on partial meniscectomy-induced osteoarthritis

Sun, Yubo, Haines, Nikkole, Roberts, Andrea, Ruffolo, Michael, Mauerhan, David R., Mihalko, Kim L., Ingram, Jane, Cox, Michael, Hanley, Edward N.

Journal:

BMC Musculoskeletal Disorders

Année:

2015

Langue:

english

Fichier:

PDF, 3.81 MB

english, 2015

7

Endothelin receptors: Receptor classification, novel receptor antagonists, and potential therapeutic targets

Eliot H. Ohlstein, John D. Elliott, Giora Z. Feuerstein, Robert R. Ruffolo Jr.

Journal:

Medicinal Research Reviews

Année:

1996

Langue:

english

Fichier:

PDF, 1.79 MB

english, 1996

8

The interaction of the enantiomers of carvedilol with α1- and β1-adrenoceptors

Andrew J. Nichols, Anthony C. Sulpizio, Daryl J. Ashton, J. Paul Hieble, Robert R. Ruffolo Jr

Journal:

Année:

1989

Langue:

english

Fichier:

PDF, 596 KB

english, 1989

9

Characterization of the hemodynamic activities of fenoldopam and its enantiomers in the dog

Lewis B. Kinter, Eugene Horner, William A. Mann, Dr. Robert R. Ruffolo Jr., Joseph Weinstock

Journal:

Année:

1990

Langue:

english

Fichier:

PDF, 680 KB

english, 1990

10

Effects of catechol ring fluorination on cardiovascular and renal activities of fenoldopam enantiomers

Lewis B. Kinter, William A. Mann, Joseph Weinstock, Robert R. Ruffolo Jr.

Journal:

Année:

1994

Langue:

english

Fichier:

PDF, 971 KB

english, 1994

11

α-adrenoceptors: Recent developments

Robert R. Ruffolo Jr., Jeffrey M. Stadel, J. Paul Hieble

Journal:

Medicinal Research Reviews

Année:

1994

Langue:

english

Fichier:

PDF, 3.19 MB

english, 1994

12

Apoptosis: a potential target for discovering novel therapies for cardiovascular diseases

Tian-Li Yue, Eliot H Ohlstein, Robert R Ruffolo Jr

Journal:

Current Opinion in Chemical Biology

Année:

1999

Langue:

english

Fichier:

PDF, 755 KB

english, 1999

13

Chirality in α- and β-adrenoceptor agonists and antagonists

Robert R. Ruffolo Jr.

Journal:

Année:

1991

Langue:

english

Fichier:

PDF, 2.36 MB

english, 1991

14

Carvedilol: A Novel Cardiovascular Drug with Multiple Actions

Robert R. Ruffolo Jr., Duane A. Boyle, David P. Brooks, Giora Z. Feuerstein, Robert P. Venuti, Mary Ann Lukas, George Poste

Journal:

Cardiovascular Therapeutics

Année:

1992

Langue:

english

Fichier:

PDF, 2.39 MB

english, 1992

15

Carvedilol: A Novel Multiple Action Antihypertensive Drug that Provides Major Organ Protection

Giora Feuerstein, Tian-Li Yue, XinLiang Ma, Robert Ruffolo Jr.

Journal:

Cardiovascular Therapeutics

Année:

1994

Langue:

english

Fichier:

PDF, 1.25 MB

english, 1994

16

Effects of a hydroxylated metabolite of the β-adrenoreceptor antagonist, carvedilol, on post-ischaemic splanchnic tissue injury

Theodore A Christopher, Bernard L Lopez, Xin-Liang Ma, Giora Z Feuerstein, Robert R Ruffolo Jr, Tian-Li Yue

Journal:

British Journal of Pharmacology

Année:

1998

Langue:

english

Fichier:

PDF, 326 KB

english, 1998

17

Congestive Heart Failure and Genomic Medicine: A Look into the 21st Century

Giora Z. Feuerstein, Robert R. Ruffolo

Journal:

Cardiovascular Drugs and Therapy

Année:

1997

Langue:

english

Fichier:

PDF, 217 KB

english, 1997

18

Pharmacology of Carvedilol: Rationale for Use in Hypertension, Coronary Artery Disease, and Congestive Heart Failure

Robert R. Ruffolo, Giora Z. Feuerstein

Journal:

Cardiovascular Drugs and Therapy

Année:

1997

Langue:

english

Fichier:

PDF, 185 KB

english, 1997

19

Antioxidant Action of Carvedilol: A Potential Role in Treatment of Heart Failure

Tian-Li Yue, Robert R. Ruffolo, Giora Feuerstein

Journal:

Heart Failure Reviews

Année:

1999

Langue:

english

Fichier:

PDF, 221 KB

english, 1999

20

Carvedilol case history: the discovery and development of the first β-blocker for the treatment of congestive heart failure

Ruffolo, Robert R, Feuerstein, Giora Z

Journal:

Expert Opinion on Drug Discovery

Année:

2006

Langue:

english

Fichier:

PDF, 91 KB

english, 2006

21

Antihypertensive activity of the non-peptide angiotensin II receptor antagonist, SK&F 108566, in rats and dogs

David P. Brooks, Todd A. Fredrickson, Joseph Weinstock, Robert R. Ruffolo, Richard M. Edwards, Miklos Gellai

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Année:

1992

Langue:

english

Fichier:

PDF, 614 KB

english, 1992

22

Pharmacologic differentiation between pre- and postjunctional α2-adrenoceptors by SK & F 104078

Robert R. Ruffolo, Anthony C. Sulpizio, Andrew J. Nichols, Robert M. DeMarinis, Paul Hieble

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Année:

1987

Langue:

english

Fichier:

PDF, 463 KB

english, 1987

23

Adrenoceptor-mediated effects of optically active catecholimidazolines in pithed rat

Robert R. Ruffolo, Popat N. Patil, Duane D. Miller

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Année:

1983

Langue:

english

Fichier:

PDF, 734 KB

english, 1983

24

Interactions of three inotropic agents, ASL-7022, dobutamine and dopamine, with α- and β-adrenoceptors in vitro

Robert R. Ruffolo, Karen Messick, J. S. Horng

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Année:

1984

Langue:

english

Fichier:

PDF, 1.15 MB

english, 1984

25

Interactions of the enantiomers of 3-O-methyldobutamine with α- and β-adrenoceptors in vitro

Robert R. Ruffolo, Karen Messick, J. S. Horng

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Année:

1985

Langue:

english

Fichier:

PDF, 977 KB

english, 1985

26

Blockade of postjunctional vascularalpha1- andalpha2-adrenoceptors in pithed rat by the enantiomers of WB-4101

Robert R. Ruffolo, Wendel L. Nelson, Emily L. Yaden

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Année:

1983

Langue:

english

Fichier:

PDF, 532 KB

english, 1983

27

Effect of chronic ethanol consumption on the pancreas of the hamster

Robert E. Weesner, John J. Ruffolo, Richard F. Murphy, Hosoon P. Dincsoy, Charles L. Mendenhall

Journal:

Digestive Diseases and Sciences

Année:

1985

Langue:

english

Fichier:

PDF, 2.61 MB

english, 1985

28

Gallbladder ejection fraction and its relationship to sphincter of Oddi dysfunction

Thomas A. Ruffolo, Stuart Sherman, Glen A. Lehman, Robert H. Hawes

Journal:

Digestive Diseases and Sciences

Année:

1994

Langue:

english

Fichier:

PDF, 323 KB

english, 1994

29

Antinociceptive activity of N-(4-hydroxyphenacetyl)-4-aminoclonidine, a novel analog of clonidine: Role of opioid receptors and alpha-adrenoceptors

Martin D. Hynes, Daphne Atlas, Robert R. Ruffolo Jr.

Journal:

Pharmacology Biochemistry and Behavior

Année:

1983

Langue:

english

Fichier:

PDF, 327 KB

english, 1983

30

Distribution and function of peripheral α-adrenoceptors in the cardiovascular system

Robert R. Ruffolo Jr.

Journal:

Pharmacology Biochemistry and Behavior

Année:

1985

Langue:

english

Fichier:

PDF, 842 KB

english, 1985

31

α-Adrenoceptors

Robert R. Ruffolo Jr., J.Paul Hieble

Journal:

Pharmacology & Therapeutics

Année:

1994

Langue:

english

Fichier:

PDF, 6.00 MB

english, 1994

32

Behaviors of youth involved in the child welfare system

Andrew Grogan-Kaylor, Mary C. Ruffolo, Robert M. Ortega, Jenell Clarke

Journal:

Child Abuse & Neglect

Année:

2008

Langue:

english

Fichier:

PDF, 180 KB

english, 2008

33

Protective Effects of Carvedilol in the Myocardium

Giora Z Feuerstein MD, Antoine Bril PhD, Robert R Ruffolo Jr, PhD

Journal:

The American Journal of Cardiology

Année:

1997

Langue:

english

Fichier:

PDF, 81 KB

english, 1997

34

Comparison of bisoprolol and carvedilol cardioprotection in a rabbit ischemia and reperfusion model

Feng Gao, Jun Chen, Bernard L Lopez, Theodore A Christopher, Juanli Gu, Paul Lysko, Robert R Ruffolo Jr., Eliot H Ohlstein, Xin L Ma, Tian-Li Yue

Journal:

European Journal of Pharmacology

Année:

2000

Langue:

english

Fichier:

PDF, 355 KB

english, 2000

35

Comparison of metoprolol and carvedilol pharmacology and cardioprotection in rabbit ischemia and reperfusion model

Giora Feuerstein, Gao-Lin Liu, Tian-Li Yue, H-Y Cheng, J.Paul Hieble, Jonathan R.S Arch, Robert R Ruffolo Jr., X.-L Ma

Journal:

European Journal of Pharmacology

Année:

1998

Langue:

english

Fichier:

PDF, 340 KB

english, 1998

36

SB 211475, a metabolite of carvedilol, reduces infarct size after myocardial ischemic and reperfusion injury in rabbits

Harald Brunvand, Gaolin Liu, Xin-Liang Ma, Tian-Li Yue, Robert R Ruffolo Jr., Giora Z Feuerstein

Journal:

European Journal of Pharmacology

Année:

1998

Langue:

english

Fichier:

PDF, 233 KB

english, 1998

37

Effects of α1-adrenoceptor antagonists on agonist and tilt-induced changes in blood pressure: relationships to uroselectivity

J.Paul Hieble, David C Kolpak, Gerald P McCafferty, Robert R Ruffolo Jr., Rodolfo Testa, Amedeo Leonardi

Journal:

European Journal of Pharmacology

Année:

1999

Langue:

english

Fichier:

PDF, 302 KB

english, 1999

38

Novel mechanisms in the treatment of heart failure: Inhibition of oxygen radicals and apoptosis by carvedilol

Giora Feuerstein, Tian-Li Yue, Xinliang Ma, Robert R. Ruffolo

Journal:

Progress in Cardiovascular Diseases

Année:

1998

Langue:

english

Fichier:

PDF, 1.02 MB

english, 1998

39

Apoptosis and Congestive Heart Failure

Giora Feuerstein, Robert R Ruffolo Jr., Tian-Li Yue

Journal:

Trends in Cardiovascular Medicine

Année:

1997

Langue:

english

Fichier:

PDF, 2.02 MB

english, 1997

40

L 1 - IMIDAZOLINE RECEPTORS: HISTORICAL PERSPECTIVE

J. Paul Hieble, Robert R. Ruffolo Jr.

Journal:

Fundamental & Clinical Pharmacology

Année:

1992

Langue:

english

Fichier:

PDF, 634 KB

english, 1992

41

Importance of receptor regulation in the pathophysiology and therapy of congestive heart failure

Robert R. Ruffolo Jr., Gregory A. Kopia

Journal:

The American Journal of Medicine

Année:

1986

Langue:

english

Fichier:

PDF, 648 KB

english, 1986

42

Biochemical correlates for the pharmacological effects of L(+)-Isomers and β-desoxy-sympathomimetic amines

Robert R. Ruffolo Jr., Duane D. Miller, Popat N. Patil

Journal:

Biochemical Pharmacology

Année:

1976

Langue:

english

Fichier:

PDF, 669 KB

english, 1976

43

Properties of 8,9-dichloro-2,3,4,5-tetrahydro-1H- 2-benzazepine, an inhibitor of norepinephrine N-methyltransferase

Ray W. Fuller, Susan Hemrick-Luecke, Richard E. Toomey, Jong-Sin Horng, Robert R. Ruffolo Jr., Bryan B. Molloy

Journal:

Biochemical Pharmacology

Année:

1981

Langue:

english

Fichier:

PDF, 777 KB

english, 1981

44

Receptor interactions of imidazolines influence of ionization constant on the diffusion of clonidine and a series of structurally related imidazolidines into and out of the central nervous system

Robert R. Ruffolo Jr., Emily L. Yaden, John S. Ward

Journal:

European Journal of Pharmacology

Année:

1982

Langue:

english

Fichier:

PDF, 670 KB

english, 1982

45

Selective α2-adrenoceptor agonist activity of the novel inotropic agent, ASL-7022: Comparison with dobutamine

Robert R. Ruffolo Jr., Emily L. Yaden

Journal:

European Journal of Pharmacology

Année:

1983

Langue:

english

Fichier:

PDF, 281 KB

english, 1983

46

Differences in the applicability of the Easson-Stedman hypothesis to the α1- and α2-adrenergic effects of phenethylamines and imidazolines

Robert R. Ruffolo Jr., Peter J. Rice, Popat N. Patil, Akihiko Hamada, Duane D. Miller

Journal:

European Journal of Pharmacology

Année:

1983

Langue:

english

Fichier:

PDF, 352 KB

english, 1983

47

Relative potency of LY141865 at dopamine DA2 and histamine H2 receptors

Robert R. Ruffolo Jr., Carl J. Shaar

Journal:

European Journal of Pharmacology

Année:

1983

Langue:

english

Fichier:

PDF, 133 KB

english, 1983

48

Systemic hemodynamic effects of dopamine, (±)-dobutamine and the (+)- and (−)-enantiomers of dobutamine in anesthetized normotensive rats

Robert R. Ruffolo Jr., Karen Messick

Journal:

European Journal of Pharmacology

Année:

1985

Langue:

english

Fichier:

PDF, 672 KB

english, 1985

49

Relationship between α2-adrenoceptor occupancy and response for B-HT 933 in canine saphenous vein

Robert R. Ruffolo Jr., Robert L. Zeid

Journal:

European Journal of Pharmacology

Année:

1985

Langue:

english

Fichier:

PDF, 361 KB

english, 1985

50

The relationship between alterations in α1-adrenoceptor reserve by phenoxybenzamine and benextramine and the sensitivity of cirazoline-induced pressor responses to inhibition by nifedipine

Andrew J. Nichols, Robert R. Ruffolo Jr.

Journal:

European Journal of Pharmacology

Année:

1986

Langue:

english

Fichier:

PDF, 379 KB

english, 1986